Resveratrol – Diabetes
In late 1999, research was published of a study that showed that type 2 diabetic participants that drank two five-ounce glasses of red wine with their meal experienced lowered incidences of the production of compounds that can produce vascular damage, an interesting result to say the least for those studying diabetes. More recently, studies on mice have shown that even low levels of resveratrol doses can improve their sensitivity to hormone insulin. The findings could lead to the development of new therapies for both prevention and treatment of type 2 diabetes. Continuing research will hopefully tell if resveratrol might have further benefits for not only type 2 diabetes and diabetic vascular disease, but other insulin disorders as well.
Resveratrol is known to activate a gene called SIRT1, and SIRT1 is linked not only to insulin secretion, but also to better insulin sensitivity in mice. Other research has found a connection between SIRT1 and glucose metabolism. Researchers have reported that insulin resistant disorders like diabetes block normal activation of SIRT1, a factor resulting in the active study of SIRT1 activating compounds, of which resveratrol in certainly a front runner.
Ongoing investigation is required before resveratrol supplementation can be responsibly approved for diabetes disorders, but early findings have given enough initial positive results to warrant further research for scientists and medical researchers alike.